Publications

2019

Lombardi, L; Shi, Y; Falanga, A; Galdiero, E; Alteriis, De E; Franci, G; Chourpa, I; Azevedo, H S; Galdiero, S

Enhancing the Potency of Antimicrobial Peptides through Molecular Engineering and Self-Assembly Journal Article

Biomacromolecules, 20 (3), pp. 1362-1374, 2019, (cited By 1).

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Lombardi, L; Falanga, A; Genio, Del V; Galdiero, S

A new hope: Self-assembling peptides with antimicrobial activity Journal Article

Pharmaceutics, 11 (4), 2019, (cited By 0).

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Mangoni, A A; Guillou, C; Eynde, J J V; Hulme, C; Jampilek, J; Li, W; Prokai-Tatrai, K; Rautio, J; Collina, S; Tuccinardi, T; Sousa, M E; Sabatier, J -M; Galdiero, S; Karaman, R; Kokotos, G; Torri, G; Luque, Javier F; Vasconcelos, Helena M; Hadjipavlou-Litina, D; Siciliano, C; Gütschow, M; Ragno, R; Gomes, P A C; Agrofoglio, L A; Muñoz-Torrero, D

Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-4 Journal Article

Molecules, pp. 1-12, 2019, (cited By 0).

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Iachetta, G; Falanga, A; Molino, Y; Masse, M; Jabès, F; Mechioukhi, Y; Laforgia, V; Khrestchatisky, M; Galdiero, S; Valiante, S

gH625-liposomes as tool for pituitary adenylate cyclase-activating polypeptide brain delivery Journal Article

Scientific Reports, 9 (1), 2019, (cited By 0).

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Djemaa, Ben S; Hervè-Aubert, K; Lajoie, L; Falanga, A; Galdiero, S; Nedellec, S; Soucè, M; Munnier, E; Chourpa, I; David, S; Allard-Vannier, E

GH625 Cell-Penetrating Peptide Promotes the Endosomal Escape of Nanovectorized siRNA in a Triple-Negative Breast Cancer Cell Line Journal Article

Biomacromolecules, 20 (8), pp. 3076-3086, 2019, (cited By 0).

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Stelitano, D; Franci, G; Chianese, A; Galdiero, S; Morelli, G; Galdiero, M

HSV membrane glycoproteins, their function in viral entry and their use in vaccine studies Journal Article

Amino Acids, Peptides and Proteins, 43 , pp. 14-43, 2019, (cited By 0).

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Pero, R; Angrisano, T; Brancaccio, M; Falanga, A; Lombardi, L; Natale, F; Laneri, S; Lombardo, B; Galdiero, S; Scudiero, O

Beta-defensins and analogs in Helicobacter pylori infections: mRNA expression levels, DNA methylation, and antibacterial activity Journal Article

PLoS ONE, 14 (9), 2019, (cited By 0).

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Mangoni, A A; Eynde, J J V; Jampilek, J; Hadjipavlou-Litina, D; Liu, H; Reynisson, J; Sousa, M E; Gomes, P A C; Prokai-Tatrai, K; Tuccinardi, T; Sabatier, J -M; Luque, F J; Rautio, J; Karaman, R; Vasconcelos, M H; Gemma, S; Galdiero, S; Hulme, C; Collina, S; GÌtschow, M; Kokotos, G; Siciliano, C; Capasso, R; Agrofoglio, L A; Ragno, R; Muñoz-Torrero, D

Breakthroughs in medicinal chemistry: New targets and mechanisms, New Drugs, New Hopes-5 Journal Article

Molecules, 24 (13), 2019, (cited By 0).

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2018

Falanga, A; Iachetta, G; Lombardi, L; Perillo, E; Lombardi, A; Morelli, G; Valiante, S; Galdiero, S

Enhanced uptake of gH625 by blood brain barrier compared to liver in vivo: characterization of the mechanism by an in vitro model and implications for delivery Journal Article

Scientific Reports, 8 (1), 2018, (cited By 1).

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de Alteriis, E; Lombardi, L; Falanga, A; Napolano, M; Galdiero, S; Siciliano, A; Carotenuto, R; Guida, M; Galdiero, E

Polymicrobial antibiofilm activity of the membranotropic peptide gH625 and its analogue Journal Article

Microbial Pathogenesis, 125 , pp. 189-195, 2018, (cited By 1).

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Djemaa, Ben S; David, S; Hervé-Aubert, K; Falanga, A; Galdiero, S; Allard-Vannier, E; Chourpa, I; Munnier, E

Formulation and in vitro evaluation of a siRNA delivery nanosystem decorated with gH625 peptide for triple negative breast cancer theranosis Journal Article

European Journal of Pharmaceutics and Biopharmaceutics, 131 , pp. 99-108, 2018, (cited By 1).

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Falanga, A; Mercurio, F A; Siciliano, A; Lombardi, L; Galdiero, S; Guida, M; Libralato, G; Leone, M; Galdiero, E

Metabolomic and oxidative effects of quantum dots-indolicidin on three generations of Daphnia magna Journal Article

Aquatic Toxicology, 198 , pp. 158-164, 2018, (cited By 3).

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de Alteriis, E; Falanga, A; Galdiero, S; Guida, M; Maselli, V; Galdiero, E

Genotoxicity of gold nanoparticles functionalized with indolicidin towards Saccharomyces cerevisiae Journal Article

Journal of Environmental Sciences (China), 66 , pp. 138-145, 2018, (cited By 6).

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Falanga, A; Galdiero, S

Peptide chemistry encounters nanomedicine: Recent applications and upcoming scenarios in cancer Journal Article

Future Medicinal Chemistry, 10 (16), 2018, (cited By 2).

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Falanga, A; Galdiero, S

Emerging therapeutic agents on the basis of naturally occurring antimicrobial peptides Journal Article

Amino Acids, Peptides and Proteins, 42 , pp. 190-227, 2018, (cited By 4).

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Falanga, A; Galdiero, M; Morelli, G; Galdiero, S

Membranotropic peptides mediating viral entry Journal Article

Peptide Science, 110 (5), 2018, (cited By 2).

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de Alteriis, E; Maselli, V; Falanga, A; Galdiero, S; Lella, Di F M; Gesuele, R; Guida, M; Galdiero, E

Efficiency of gold nanoparticles coated with the antimicrobial peptide indolicidin against biofilm formation and development of Candida spp. clinical isolates Journal Article

Infection and Drug Resistance, 11 , pp. 915-925, 2018, (cited By 5).

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Tudisco, C; Cambria, M T; Giuffrida, A E; Sinatra, F; Anfuso, C D; Lupo, G; Caporarello, N; Falanga, A; Galdiero, S; Oliveri, V; Satriano, C; Condorelli, G G

Comparison Between Folic Acid and gH625 Peptide-Based Functionalization of Fe3O4 Magnetic Nanoparticles for Enhanced Cell Internalization Journal Article

Nanoscale Research Letters, 13 , 2018, (cited By 2).

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Mangoni, A A; Tuccinardi, T; Collina, S; Eynde, Vanden J J; oz-Torrero, Mu D; Karaman, R; Siciliano, C; de Sousa, Emília M; Prokai-Tatrai, K; Rautio, J; Guillou, C; tschow, M G; Galdiero, S; Liu, H; Agrofoglio, L A; Sabatier, J -M; Hulme, C; Kokotos, G; You, Q; Gomes, P A C

Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-3 Journal Article

Molecules, 23 (7), 2018, (cited By 0).

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2017

Galdiero, S; Gomes, P A C

Peptide-based drugs and drug delivery systems Journal Article

Molecules, 22 (12), 2017, (cited By 1).

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Falanga, A; Valiante, S; Galdiero, E; Franci, G; Scudiero, O; Morelli, G; Galdiero, S

Dimerization in tailoring uptake efficacy of the HSV-1 derived membranotropic peptide gH625 Journal Article

Scientific Reports, 7 (1), 2017, (cited By 5).

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García-Gallego, S; Franci, G; Falanga, A; Gómez, R; Folliero, V; Galdiero, S; Mata, De La F J; Galdiero, M

Function oriented molecular design: Dendrimers as novel antimicrobials Journal Article

Molecules, 22 (10), 2017, (cited By 8).

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Perillo, E; Hervé-Aubert, K; Allard-Vannier, E; Falanga, A; Galdiero, S; Chourpa, I

Synthesis and in vitro evaluation of fluorescent and magnetic nanoparticles functionalized with a cell penetrating peptide for cancer theranosis Journal Article

Journal of Colloid and Interface Science, 499 , pp. 209-217, 2017, (cited By 16).

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Franci, G; Falanga, A; Zannella, C; Folliero, V; Martora, F; Galdiero, M; Galdiero, S; Morelli, G; Galdiero, M

Infectivity inhibition by overlapping synthetic peptides derived from the gH/gL heterodimer of herpes simplex virus type 1 Journal Article

Journal of Peptide Science, 23 (4), pp. 311-319, 2017, (cited By 1).

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Kaufman, E A; Tarallo, R; Falanga, A; Galdiero, S; Weck, M

Generation effect of Newkome dendrimers on cellular uptake Journal Article

Polymer, 113 , pp. 67-73, 2017, (cited By 2).

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Lombardi, L; Stellato, M I; Oliva, R; Falanga, A; Galdiero, M; Petraccone, L; DÉrrico, G; Santis, De A; Galdiero, S; Vecchio, Del P

Antimicrobial peptides at work: Interaction of myxinidin and its mutant WMR with lipid bilayers mimicking the P. aeruginosa and E. coli membranes Journal Article

Scientific Reports, 7 , 2017, (cited By 15).

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Falanga, A; Nigro, E; Biasi, De M G; Daniele, A; Morelli, G; Galdiero, S; Scudiero, O

Cyclic peptides as novel therapeutic microbicides: Engineering of human defensin mimetics Journal Article

Molecules, 22 (7), 2017, (cited By 13).

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Maselli, V; Siciliano, A; Giorgio, A; Falanga, A; Galdiero, S; Guida, M; Fulgione, D; Galdiero, E

Multigenerational effects and DNA alterations of QDs-Indolicidin on Daphnia magna Journal Article

Environmental Pollution, 224 , pp. 597-605, 2017, (cited By 11).

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Galdiero, E; Falanga, A; Siciliano, A; Maselli, V; Guida, M; Carotenuto, R; Tussellino, M; Lombardi, L; Benvenuto, G; Galdiero, S

Daphnia magna and Xenopus laevis as in vivo models to probe toxicity and uptake of quantum dots functionalized with gH625 Journal Article

International Journal of Nanomedicine, 12 , pp. 2717-2731, 2017, (cited By 13).

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Falanga, A; Lombardi, L; Tarallo, R; Franci, G; Perillo, E; Palomba, L; Galdiero, M; Pontoni, D; Fragneto, G; Weck, M; Galdiero, S

The intriguing journey of gH625-dendrimers Journal Article

RSC Advances, 7 (15), pp. 9106-9114, 2017, (cited By 3).

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2016

Galdiero, E; Siciliano, A; Maselli, V; Gesuele, R; Guida, M; Fulgione, D; Galdiero, S; Lombardi, L; Falanga, A

An integrated study on antimicrobial activity and ecotoxicity of quantum dots and quantum dots coated with the antimicrobial peptide indolicidin Journal Article

International Journal of Nanomedicine, 11 , pp. 4199-4211, 2016, (cited By 19).

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Falanga, A; Lombardi, L; Franci, G; Vitiello, M; Iovene, M R; Morelli, G; Galdiero, M; Galdiero, S

Marine antimicrobial peptides: Nature provides templates for the design of novel compounds against pathogenic bacteria Journal Article

International Journal of Molecular Sciences, 17 (5), 2016, (cited By 20).

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Rai, M; Deshmukh, S D; Ingle, A P; Gupta, I R; Galdiero, M; Galdiero, S

Metal nanoparticles: The protective nanoshield against virus infection Journal Article

Critical Reviews in Microbiology, 42 (1), pp. 46-56, 2016, (cited By 19).

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Zappavigna, S; Misso, G; Falanga, A; Perillo, E; Novellino, E; Galdiero, M; Grieco, P; Caraglia, M; Galdiero, S

Nanocarriers conjugated with cell penetrating peptides: New Trojan horses by modern ulysses Journal Article

Current Pharmaceutical Biotechnology, 17 (8), pp. 700-722, 2016, (cited By 8).

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Perillo, E; Porto, S; Falanga, A; Zappavigna, S; Stiuso, P; Tirino, V; Desiderio, V; Papaccio, G; Galdiero, M; Giordano, A; Galdiero, S; Caraglia, M

Liposome armed with herpes virus-derived gH625 peptide to overcome doxorubicin resistance in lung adenocarcinoma cell lines Journal Article

Oncotarget, 7 (4), pp. 4077-4092, 2016, (cited By 12).

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2015

Nigro, E; Colavita, I; Sarnataro, D; Scudiero, O; Zambrano, G; Granata, V; Daniele, A; Carotenuto, A; Galdiero, S; Folliero, V; Galdiero, M; Urbanowicz, R A; Ball, J K; Salvatore, F; Pessi, A

An ancestral host defence peptide within human β-defensin 3 recapitulates the antibacterial and antiviral activity of the full-length molecule Journal Article

Scientific Reports, 5 , 2015, (cited By 13).

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Caso, J V; Russo, L; Palmieri, M; Malgieri, G; Galdiero, S; Falanga, A; Isernia, C; Iacovino, R

Investigating the inclusion properties of aromatic amino acids complexing beta-cyclodextrins in model peptides Journal Article

Amino Acids, 47 (10), pp. 2215-2227, 2015, (cited By 39).

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Falanga, A; Galdiero, M; Galdiero, S

Membranotropic cell penetrating peptides: The outstanding journey Journal Article

International Journal of Molecular Sciences, 16 (10), pp. 25323-25337, 2015, (cited By 25).

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Scudiero, O; Nigro, E; Cantisani, M; Colavita, I; Leone, M; Mercurio, F A; Galdiero, M; Pessi, A; Daniele, A; Salvatore, F; Galdiero, S

Design and activity of a cyclic mini-β-defensin analog: A novel antimicrobial tool Journal Article

International Journal of Nanomedicine, 10 , pp. 6523-6539, 2015, (cited By 12).

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Guarnieri, D; Muscetti, O; Falanga, A; Fusco, S; Belli, V; Perillo, E; Battista, E; Panzetta, V; Galdiero, S; Netti, P A

Surface decoration with gH625-membranotropic peptides as a method to escape the endo-lysosomal compartment and reduce nanoparticle toxicity Journal Article

Nanotechnology, 26 (41), 2015, (cited By 8).

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Notomista, E; Falanga, A; Fusco, S; Pirone, L; Zanfardino, A; Galdiero, S; Varcamonti, M; Pedone, E; Contursi, P

The identification of a novel Sulfolobus islandicus CAMP-like peptide points to archaeal microorganisms as cell factories for the production of antimicrobial molecules Journal Article

Microbial Cell Factories, 14 (1), 2015, (cited By 12).

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Galdiero, E; Maselli, V; Falanga, A; Gesuele, R; Galdiero, S; Fulgione, D; Guida, M

Integrated analysis of the ecotoxicological and genotoxic effects of the antimicrobial peptide melittin on Daphnia magna and Pseudokirchneriella subcapitata Journal Article

Environmental Pollution, 203 , pp. 145-152, 2015, (cited By 11).

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Perillo, E; Allard-Vannier, E; Falanga, A; Stiuso, P; Vitiello, M T; Galdiero, M; Galdiero, S; Chourpa, I

Quantitative and qualitative effect of gH625 on the nanoliposome-mediated delivery of mitoxantrone anticancer drug to HeLa cells Journal Article

International Journal of Pharmaceutics, 488 (1-2), pp. 59-66, 2015, (cited By 19).

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Ringhieri, P; Diaferia, C; Galdiero, S; Palumbo, R; Morelli, G; Accardo, A

Liposomal doxorubicin doubly functionalized with CCK8 and R8 peptide sequences for selective intracellular drug delivery Journal Article

Journal of Peptide Science, 21 (5), pp. 415-425, 2015, (cited By 12).

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Vitiello, G; Falanga, A; Petruk, A A; Merlino, A; Fragneto, G; Paduano, L; Galdiero, S; DÉrrico, G

Fusion of raft-like lipid bilayers operated by a membranotropic domain of the HSV-type i glycoprotein gH occurs through a cholesterol-dependent mechanism Journal Article

Soft Matter, 11 (15), pp. 3003-3016, 2015, (cited By 26).

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Valiante, S; Falanga, A; Cigliano, L; Iachetta, G; Busiello, R A; Marca, La V; Galdiero, M; Lombardi, A; Galdiero, S

Peptide gH625 enters into neuron and astrocyte cell lines and crosses the blood–brain barrier in rats Journal Article

International Journal of Nanomedicine, 10 , pp. 1885-1898, 2015, (cited By 15).

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Guarnieri, D; Biondi, M; Yu, H; Belli, V; Falanga, A P; Cantisani, M; Galdiero, S; Netti, P A

Tumor-activated prodrug (TAP)-conjugated nanoparticles with cleavable domains for safe doxorubicin delivery Journal Article

Biotechnology and Bioengineering, 112 (3), pp. 601-611, 2015, (cited By 17).

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Borchmann, D E; Tarallo, R; Avendano, S; Falanga, A; Carberry, T P; Galdiero, S; Weck, M

Membranotropic peptide-functionalized poly(lactide)- graft -poly(ethylene glycol) brush copolymers for intracellular delivery Journal Article

Macromolecules, 48 (4), pp. 942-949, 2015, (cited By 14).

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Galdiero, S; Falanga, A; Morelli, G; Galdiero, M

GH625: A milestone in understanding the many roles of membranotropic peptides Journal Article

Biochimica et Biophysica Acta - Biomembranes, (Part A), pp. 16-25, 2015, (cited By 29).

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Galdiero, S; Falanga, A; Berisio, R; Grieco, P; Morelli, G; Galdiero, M

Antimicrobial peptides as an opportunity against bacterial diseases Journal Article

Current Medicinal Chemistry, 22 (14), pp. 1665-1677, 2015, (cited By 36).

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Franci, G; Falanga, A; Galdiero, S; Palomba, L; Rai, M; Morelli, G; Galdiero, M

Silver nanoparticles as potential antibacterial agents Journal Article

Molecules, 20 (5), pp. 8856-8874, 2015, (cited By 360).

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2014

Falanga, A; Tarallo, R; Carberry, T; Galdiero, M; Weck, M; Galdiero, S

Elucidation of the interaction mechanism with liposomes of gH625-peptide functionalized dendrimers Journal Article

PLoS ONE, 9 (11), 2014, (cited By 13).

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Rai, M; Kon, K; Ingle, A; Duran, N; Galdiero, S; Galdiero, M

Broad-spectrum bioactivities of silver nanoparticles: The emerging trends and future prospects Journal Article

Applied Microbiology and Biotechnology, 98 (5), pp. 1951-1961, 2014, (cited By 127).

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Galdiero, S; Falanga, A; Vitiello, M; Grieco, P; Caraglia, M; Morelli, G; Galdiero, M

Exploitation of viral properties for intracellular delivery Journal Article

Journal of Peptide Science, 20 (7), pp. 468-478, 2014, (cited By 19).

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Santos, Dos C A; Seckler, M M; Ingle, A P; Gupta, I; Galdiero, S; Galdiero, M; Gade, A; Rai, M

Silver nanoparticles: Therapeutical uses, toxicity, and safety issues Journal Article

Journal of Pharmaceutical Sciences, 103 (7), pp. 1931-1944, 2014, (cited By 146).

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Cantisani, M; Finamore, E; Mignogna, E; Falanga, A; Nicoletti, G F; Pedone, C; Morelli, G; Leone, M; Galdiero, M; Galdiero, S

Structural insights into and activity analysis of the antimicrobial peptide myxinidin Journal Article

Antimicrobial Agents and Chemotherapy, 58 (9), pp. 5280-5290, 2014, (cited By 29).

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2013

Cantisani, M; Falanga, A; Incoronato, N; Russo, L; Simone, De A; Morelli, G; Berisio, R; Galdiero, M; Galdiero, S

Conformational modifications of gB from herpes simplex virus type 1 analyzed by synthetic peptides Journal Article

Journal of Medicinal Chemistry, 56 (21), pp. 8366-8376, 2013, (cited By 6).

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Gaikwad, S; Ingle, A; Gade, A; Rai, M; Falanga, A; Incoronato, N; Russo, L; Galdiero, S; Galdiero, M

Antiviral activity of mycosynthesized silver nanoparticles against herpes simplex virus and human parainfluenza virus type 3 Journal Article

International Journal of Nanomedicine, 8 , pp. 4303-4314, 2013, (cited By 75).

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Cantisani, M; Leone, M; Mignogna, E; Kampanaraki, K; Falanga, A; Morelli, G; Galdiero, M; Galdiero, S

Structure-activity relations of myxinidin, an antibacterial peptide derived from the epidermal mucus of hagfish Journal Article

Antimicrobial Agents and Chemotherapy, 57 (11), pp. 5665-5673, 2013, (cited By 20).

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Galdiero, S; Falanga, A; Cantisani, M; Vitiello, M; Morelli, G; Galdiero, M

Peptide-lipid interactions: Experiments and applications Journal Article

International Journal of Molecular Sciences, 14 (9), pp. 18758-18789, 2013, (cited By 44).

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Vitiello, G; Fragneto, G; Petruk, A A; Falanga, A; Galdiero, S; D'Ursi, A M; Merlino, A; DÉrrico, G

Cholesterol modulates the fusogenic activity of a membranotropic domain of the FIV glycoprotein gp36 Journal Article

Soft Matter, 9 (28), pp. 6442-6456, 2013, (cited By 22).

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Smaldone, G; Falanga, A; Capasso, D; Guarnieri, D; Correale, S; Galdiero, M; Netti, P A; Zollo, M; Galdiero, S; Gaetano, Di S; Pedone, E

gH625 is a viral derived peptide for effective delivery of intrinsically disordered proteins Journal Article

International Journal of Nanomedicine, 8 , pp. 2555-2565, 2013, (cited By 19).

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Falanga, A; Tarallo, R; Galdiero, E; Cantisani, M; Galdiero, M; Galdiero, S

Review of a viral peptide nanosystem for intracellular delivery Journal Article

Journal of Nanophotonics, 7 (1), 2013, (cited By 9).

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Scudiero, O; Galdiero, S; Nigro, E; Vecchio, Del L; Noto, Di R; Cantisani, M; Colavita, I; Galdiero, M; Cassiman, J -J; Daniele, A; Pedone, C; Salvatore, F

Chimeric beta-defensin analogs, including the novel 3NI analog, display salt-resistant antimicrobial activity and lack toxicity in human epithelial cell lines Journal Article

Antimicrobial Agents and Chemotherapy, 57 (4), pp. 1701-1708, 2013, (cited By 26).

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Antonellis, De P; Liguori, L; Falanga, A; Carotenuto, M; Ferrucci, V; Andolfo, I; Marinaro, F; Scognamiglio, I; Virgilio, A; Rosa, De G; Galeone, A; Galdiero, S; Zollo, M

MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines Journal Article

Naunyn-Schmiedeberg's Archives of Pharmacology, 386 (4), pp. 287-302, 2013, (cited By 21).

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Guarnieri, D; Falanga, A; Muscetti, O; Tarallo, R; Fusco, S; Galdiero, M; Galdiero, S; Netti, P A

Shuttle-mediated nanoparticle delivery to the blood-brain barrier Journal Article

Small, 9 (6), pp. 853-862, 2013, (cited By 67).

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Galdiero, S; Falanga, A; Tarallo, R; Russo, L; Galdiero, E; Cantisani, M; Morelli, G; Galdiero, M

Peptide inhibitors against herpes simplex virus infections Journal Article

Journal of Peptide Science, 19 (3), pp. 148-158, 2013, (cited By 28).

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Tarallo, R; Carberry, T P; Falanga, A; Vitiello, M; Galdiero, S; Galdiero, M; Weck, M

Dendrimers functionalized with membrane-interacting peptides for viral inhibition Journal Article

International Journal of Nanomedicine, 8 , pp. 521-534, 2013, (cited By 25).

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2012

Cantisani, M; Vitiello, M; Falanga, A; Finamore, E; Galdiero, M; Galdiero, S

Peptides complementary to the active loop of porin P2 from Haemophilus influenzae modulate its activity Journal Article

International Journal of Nanomedicine, 7 , pp. 2361-2371, 2012, (cited By 9).

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Galdiero, S; Falanga, A; Cantisani, M; Tarallo, R; della Pepa, M E; DÓriano, V; Galdiero, M

Microbe-Host interactions: Structure and role of Gram-negative bacterial Porins Journal Article

Current Protein and Peptide Science, 13 (8), pp. 843-854, 2012, (cited By 71).

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Carberry, T P; Tarallo, R; Falanga, A; Finamore, E; Galdiero, M; Weck, M; Galdiero, S

Dendrimer functionalization with a membrane-interacting domain of herpes simplex virus type 1: Towards intracellular delivery Journal Article

Chemistry - A European Journal, 18 (43), pp. 13678-13685, 2012, (cited By 42).

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Galdiero, S; Russo, L; Falanga, A; Cantisani, M; Vitiello, M; Fattorusso, R; Malgieri, G; Galdiero, M; Isernia, C

Structure and orientation of the gH625-644 membrane interacting region of herpes simplex virus type 1 in a membrane mimetic system Journal Article

Biochemistry, 51 (14), pp. 3121-3128, 2012, (cited By 27).

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Esposito, C; Cantisani, M; DÁuria, G; Falcigno, L; Pedone, E; Galdiero, S; Berisio, R

Mapping key interactions in the dimerization process of HBHA from Mycobacterium tuberculosis, insights into bacterial agglutination Journal Article

FEBS Letters, 586 (6), pp. 659-667, 2012, (cited By 7).

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Vitiello, M; Galdiero, M; Finamore, E; Galdiero, S; Galdiero, M

NF-κB as a potential therapeutic target in microbial diseases Journal Article

Molecular BioSystems, 8 (4), pp. 1108-1120, 2012, (cited By 27).

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Falanga, A; Tarallo, R; Vitiello, G; Vitiello, M; Perillo, E; Cantisani, M; DÉrrico, G; Galdiero, M; Galdiero, S

Biophysical characterization and membrane interaction of the two fusion loops of glycoprotein b from herpes simplex type i virus Journal Article

PLoS ONE, 7 (2), 2012, (cited By 29).

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Galdiero, S; Vitiello, M; Falanga, A; Cantisani, M; Incoronato, N; Galdiero, M

Intracellular delivery: Exploiting viral membranotropic peptides Journal Article

Current Drug Metabolism, 13 (1), pp. 93-104, 2012, (cited By 34).

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Galdiero, S; Vitiello, M; Finamore, E; Mansi, R; Galdiero, M; Morelli, G; Tesauro, D

Activation of monocytic cells by immunostimulatory lipids conjugated to peptide antigens Journal Article

Molecular BioSystems, 8 (12), pp. 3166-3177, 2012, (cited By 2).

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2011

DÉrrico, G; Ercole, C; Lista, M; Pizzo, E; Falanga, A; Galdiero, S; Spadaccini, R; Picone, D

Enforcing the positive charge of N-termini enhances membrane interaction and antitumor activity of bovine seminal ribonuclease Journal Article

Biochimica et Biophysica Acta - Biomembranes, 1808 (12), pp. 3007-3015, 2011, (cited By 19).

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Falanga, A; Vitiello, M T; Cantisani, M; Tarallo, R; Guarnieri, D; Mignogna, E; Netti, P; Pedone, C; Galdiero, M; Galdiero, S

A peptide derived from herpes simplex virus type 1 glycoprotein H: Membrane translocation and applications to the delivery of quantum dots Journal Article

Nanomedicine: Nanotechnology, Biology, and Medicine, 7 (6), pp. 925-934, 2011, (cited By 54).

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Tarallo, R; Accardo, A; Falanga, A; Guarnieri, D; Vitiello, G; Netti, P; DÉrrico, G; Morelli, G; Galdiero, S

Clickable functionalization of liposomes with the gH625 peptide from herpes simplex virus type i for intracellular drug delivery Journal Article

Chemistry - A European Journal, 17 (45), pp. 12659-12668, 2011, (cited By 52).

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Galdiero, S; Falanga, A; Vitiello, M; Cantisani, M; Marra, V; Galdiero, M

Silver nanoparticles as potential antiviral agents Journal Article

Molecules, 16 (10), pp. 8894-8918, 2011, (cited By 216).

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Vitiello, G; Falanga, A; Galdiero, M; Marsh, D; Galdiero, S; DÉrrico, G

Lipid composition modulates the interaction of peptides deriving from herpes simplex virus type i glycoproteins B and H with biomembranes Journal Article

Biochimica et Biophysica Acta - Biomembranes, 1808 (10), pp. 2517-2526, 2011, (cited By 19).

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2010

Vitiello, M; Finamore, E; Falanga, A; Raieta, K; Cantisani, M; Galdiero, F; Pedone, C; Galdiero, M; Galdiero, S

Viral fusion peptides induce several signal transduction pathway activations that are essential for interleukin-10 and beta-interferon production Journal Article

Intervirology, 53 (6), pp. 381-389, 2010, (cited By 2).

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Scudiero, O; Galdiero, S; Cantisani, M; Noto, Di R; Vitiello, M; Galdiero, M; Naclerio, G; Cassiman, J -J; Pedone, C; Castaldo, G; Salvatore, F

Novel synthetic, salt-resistant analogs of human beta-defensins 1 and 3 endowed with enhanced antimicrobial activity Journal Article

Antimicrobial Agents and Chemotherapy, 54 (6), pp. 2312-2322, 2010, (cited By 78).

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Galdiero, S; Falanga, A; Vitiello, M; Raiola, L; Russo, L; Pedone, C; Isernia, C; Galdiero, M

The presence of a single N-terminal histidine residue enhances the fusogenic properties of a membranotropic peptide derived from herpes simplex virus type 1 glycoprotein H Journal Article

Journal of Biological Chemistry, 285 (22), pp. 17123-17136, 2010, (cited By 46).

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Galdiero, S; Falanga, A; Vitiello, G; Vitiello, M; Pedone, C; DÉrrico, G; Galdiero, M

Role of membranotropic sequences from herpes simplex virus type I glycoproteins B and H in the fusion process Journal Article

Biochimica et Biophysica Acta - Biomembranes, 1798 (3), pp. 579-591, 2010, (cited By 41).

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Severino, V; Chambery, A; Vitiello, M; Cantisani, M; Galdiero, S; Galdiero, M; Malorni, L; Maro, Di A; Parente, A

Proteomic analysis of human U937 cell line activation mediated by Haemophilus influenzae type b P2 porin and its surface-exposed loop 7 Journal Article

Journal of Proteome Research, 9 (2), pp. 1050-1062, 2010, (cited By 21).

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2009

Galdiero, S

Protein and Peptide Letters: Editorial Journal Article

Protein and Peptide Letters, 16 (7), pp. 711, 2009, (cited By 6).

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Falanga, A; Cantisani, M; Pedone, C; Galdiero, S

Membrane fusion and fission: Enveloped viruses Journal Article

Protein and Peptide Letters, 16 (7), pp. 751-759, 2009, (cited By 30).

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2008

Galdiero, S; Falanga, A; Vitiello, M; Raiola, L; Fattorusso, R; Browne, H; Pedone, C; Isernia, C; Galdiero, M

Analysis of a membrane interacting region of herpes simplex virus type 1 glycoprotein H Journal Article

Journal of Biological Chemistry, 283 (44), pp. 29993-30009, 2008, (cited By 47).

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Galdiero, S; Falanga, A; Vitiello, M; D'Isanto, M; Cantisani, M; Kampanaraki, A; Benedetti, E; Browne, H; Galdiero, M

Peptides containing membrane-interacting motifs inhibit herpes simplex virus type 1 infectivity Journal Article

Peptides, 29 (9), pp. 1461-1471, 2008, (cited By 38).

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Vitiello, M; Galdiero, S; D'Isanto, M; DÁmico, M; Filippo, Di C; Cantisani, M; Galdiero, M; Pedone, C

Pathophysiological changes of gram-negative bacterial infection can be reproduced by a synthetic peptide mimicking loop L7 sequence of Haemophilus influenzae porin Journal Article

Microbes and Infection, 10 (6), pp. 657-663, 2008, (cited By 3).

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Galdiero, S; Vitiello, M; D'Isanto, M; Falanga, A; Cantisani, M; Browne, H; Pedone, C; Galdiero, M

The identification and characterization of fusogenic domains in herpes virus glycoprotein B molecules Journal Article

ChemBioChem, 9 (5), pp. 758-767, 2008, (cited By 41).

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2007

Galdiero, S; Falanga, A; Vitiello, M; D'Isanto, M; Collins, C; Orrei, V; Browne, H; Pedone, C; Galdiero, M

Evidence for a role of the membrane-proximal region of herpes simplex virus type 1 glycoprotein H in membrane fusion and virus inhibition Journal Article

ChemBioChem, 8 (8), pp. 885-895, 2007, (cited By 45).

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Galdiero, S; Galdiero, M; Pedone, C

β-barrel membrane bacterial proteins: Structure, function, assembly and interaction with lipids Journal Article

Current Protein and Peptide Science, 8 (1), pp. 63-82, 2007, (cited By 51).

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2006

Bona, Dalla A; Formaggio, F; Peggion, C; Kaptein, B; Broxterman, Q B; Galdiero, S; Galdiero, M; Vitiello, M; Benedetti, E; Toniolo, C

Synthesis, conformation, and bioactivity of novel analogues of the antiviral lipopeptide halovir A Journal Article

Journal of Peptide Science, 12 (12), pp. 748-757, 2006, (cited By 5).

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Galdiero, S; Vitielo, M; D'Isanto, M; Falanga, A; Collins, C; Raieta, K; Pedone, C; Browne, H; Galdiero, M

Analysis of synthetic peptides from heptad-repeat domains of herpes simplex virus type 1 glycoproteins H and B Journal Article

Journal of General Virology, 87 (5), pp. 1085-1097, 2006, (cited By 47).

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Galdiero, S; Vitiello, M; Amodeo, P; D'Isanto, M; Cantisani, M; Pedone, C; Galdiero, M

Structural requirements for proinflammatory activity of porin P2 loop 7 from Haemophilus influenzae Journal Article

Biochemistry, 45 (14), pp. 4491-4501, 2006, (cited By 16).

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2005

Galdiero, S; Falanga, A; Vitiello, M; Browne, H; Pedone, C; Galdiero, M

Fusogenic domains in herpes simplex virus type 1 glycoprotein H Journal Article

Journal of Biological Chemistry, 280 (31), pp. 28632-28643, 2005, (cited By 92).

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Saviano, M; Isernia, C; Bassarello, C; Lello, Di P; Galdiero, S; Mierke, D F; Benedetti, E; Pedone, C

Conformational analysis by NMR and distance geometry techniques of a peptide mimetic of the third helix of the Antennapedia homeodomain Journal Article

Journal of Peptide Research, 65 (2), pp. 200-208, 2005, (cited By 0).

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2004

Galdiero, S; Vitiello, M; D'Isanto, M; Niola, Di E; Peluso, L; Raieta, K; Pedone, C; Galdiero, M; Benedetti, E

Induction of signaling pathways by herpes simplex virus type 1 through glycoprotein H peptides Journal Article

Biopolymers - Peptide Science Section, 76 (6), pp. 494-502, 2004, (cited By 7).

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Galdiero, S; Gouaux, E

High resolution crystallographic studies of α-hemolysin-phospholipid complexes define heptamer-lipid head group interactions: Implication for understanding protein-lipid interactions Journal Article

Protein Science, 13 (6), pp. 1503-1511, 2004, (cited By 54).

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2003

Galdiero, M; Vitiello, M; Galdiero, S

Eukaryotic cell signaling and transcriptional activation induced by bacterial porins Journal Article

FEMS Microbiology Letters, 226 (1), pp. 57-64, 2003, (cited By 20).

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Bartolucci, S; Simone, De G; Galdiero, S; Improta, R; Menchise, V; Pedone, C; Pedone, E; Saviano, M

An integrated structural and computational study of the thermostability of two thioredoxin mutants from Alicyclobacillus acidocaldarius Journal Article

Journal of Bacteriology, 185 (14), pp. 4285-4289, 2003, (cited By 10).

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Galdiero, S; Capasso, D; Vitiello, M; D'Isanto, M; Pedone, C; Galdiero, M

Role of surface-exposed loops of Haemophilus influenzae protein P2 in the mitogen-activated protein kinase cascade Journal Article

Infection and Immunity, 71 (5), pp. 2798-2809, 2003, (cited By 31).

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2002

Galdiero, M; Vitiello, M; Sanzari, E; D'Isanto, M; Tortora, A; Longanella, A; Galdiero, S

Porins from Salmonella enterica serovar Typhimurium activate the transcription factors activating protein 1 and NF-κB through the Raf-1-mitogen-activated protein kinase cascade Journal Article

Infection and Immunity, 70 (2), pp. 558-568, 2002, (cited By 37).

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2000

Simone, De G; Galdiero, S; Manco, G; Lang, D; Rossi, M; Pedone, C

A snapshot of a transition state analogue of a novel thermophilic esterase belonging to the subfamily of mammalian hormone-sensitive lipase Journal Article

Journal of Molecular Biology, 303 (5), pp. 761-771, 2000, (cited By 103).

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Lombardi, A; Simone, De G; Galdiero, S; Nastri, F; Costanzo, Di L; Makihira, K; Yamada, T; Pavone, V

The crystal structure of Afc-containing peptides Journal Article

Biopolymers, 53 (2), pp. 150-160, 2000, (cited By 11).

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Simone, De G; Lombardi, A; Galdiero, S; Nastri, F; Costanzo, Di L; Gohda, S; Sano, A; Yamada, T; Pavone, V

The crystal structure of a Dcp-containing peptide Journal Article

Biopolymers, 53 (2), pp. 182-188, 2000, (cited By 13).

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1999

Simone, De G; Manco, G; Galdiero, S; Lombardi, A; Rossi, M; Pavone, V

Crystallization and preliminary X-ray diffraction studies of the carboxylesterase EST2 from Alicyclobacillus acidocaldarius Journal Article

Acta Crystallographica Section D: Biological Crystallography, 55 (7), pp. 1348-1349, 1999, (cited By 14).

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Lombardi, A; Simone, De G; Galdiero, S; Staiano, N; Nastri, F; Pavone, V

From natural to synthetic multisite thrombin inhibitors Journal Article

Biopolymers - Peptide Science Section, 51 (1), pp. 19-39, 1999, (cited By 21).

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Lombardi, A; Simone, De G; Nastri, F; Galdiero, S; Morte, Della R; Staiano, N; Pedone, C; Bolognesi, M; Pavone, V

The crystal structure of α-thrombin-hirunorm IV complex reveals a novel specificity site recognition mode Journal Article

Protein Science, 8 (1), pp. 91-95, 1999, (cited By 8).

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1998

Pavone, V; Simone, De G; Nastri, F; Galdiero, S; Staiano, N; Lombardi, A; Pedone, C

Multiple binding mode of reversible synthetic thrombin inhibitors. A comparative structural analysis Journal Article

Biological Chemistry, 379 (8-9), pp. 987-1006, 1998, (cited By 23).

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Simone, De G; Lombardi, A; Galdiero, S; Nastri, F; Morte, Della R; Staiano, N; Pedone, C; Bolognesi, M; Pavone, V

Hirunorms are true hirudin mimetics. The crystal structure of human α- thrombin-hirunorm V complex Journal Article

Protein Science, 7 (2), pp. 243-253, 1998, (cited By 17).

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1997

Gatos, M; Formaggio, F; Crisma, M; Valle, G; Toniolo, C; Bonora, G M; Saviano, M; Iacovino, R; Menchise, V; Galdiero, S; Pedone, C; Benedetti, E

Conformational characterization of peptides rich in the cycloaliphatic Cα,α-disubstituted glycine 1-Amino-cyclononane-1-carboxylic acid Journal Article

Journal of Peptide Science, 3 (5), pp. 367-382, 1997, (cited By 11).

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1996

Blasio, Di B; Galdiero, S; Saviano, M; Simone, De G; Benedetti, E; Pedone, C; Gibbons, W A; Deschenaux, R; Rizzarelli, E; Vecchio, G

Functionalized cyclodextrins: Synthesis and structural characterization of 6-deoxy-6-4-[N-tert-butoxycarbonyl-2-aminoethyl]-imidazolyl-cyclomaltoheptaose Journal Article

Supramolecular Chemistry, 7 (1), pp. 47-54, 1996, (cited By 17).

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Blasio, Di B; Galdiero, S; Saviano, M; Pedone, C; Benedetti, E; Rizzarelli, E; Pedotti, S; Vecchio, G; Gibbons, W A

Synthesis and structural characterization of 6I,6II-diamino-6I,6 II-dideoxy-cyclomaltoheptaose, a difunctionalized β-cyclodextrin Journal Article

Carbohydrate Research, 282 (1), pp. 41-52, 1996, (cited By 22).

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Santini, A; Blasio, Di B; Galdiero, S; Iacovino, R; Pedone, C; Benedetti, E; Crisma, M; Toniolo, C

Molecular and crystal structures of two terminally-blocked Ac<inf>5</inf>c homo-oligopeptides Journal Article

Zeitschrift fur Kristallographie - New Crystal Structures, 211 (9), pp. 616-621, 1996, (cited By 4).

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Galdiero S, Falanga A, Cantisani M, Ingle A, Galdiero M, Rai M. Silver nanoparticles as novel antibacterial and antiviral agents. In: Torchilin V, ed. Frontiers of Nanobiomedical Research. A WSPC Reference on The State of the Art: Fundamentals, Main Applications and Vision for the Future. Vol 3. World Scientific Publishing Co; 2014:1-30.

Galdiero M, Cantisani M, Tarallo R, Falanga A, Galdiero S, Dr. Fernandez. Septic shock by gram-negative infections: role of outer membrane proteins. In: Severe Sepsis and Septic Shock – Understanding a Serious Killer. Intech; 2012:27-46.

Falanga A, Galdiero S. Emerging therapeutic agents on the basis of naturally occurring antimicrobial peptides. In: Hudecz Ferenc , Ryadnov M, eds. Amino Acids, Peptides and Proteins. Vol 42. Royal Society of Chemistry; 2018:190-227.

Franci G, Palomba L, Falanga A, et al. The microbiology of Respiratory System Infections. In: Kon K, Rai Mahendra , eds. The Microbiology of Respiratory System Infections. Vol 1. Elsevier; 2016:1-32.

Galdiero S, Cantisani M, Falanga A, Vitiello M, Galdiero M, Dunn B. b-barrel membrane bacterial proteins: structure, function, assembly and interaction with lipids. In: Advances in Protein & Peptide Sciences. Vol 1. Bentham Science Editor; 2013:1-65.

Castaldo G, Galdiero S, Pedone C, Salvatore F, Scudiero O. Synthetic analogs of human b-defensin having antimicrobial, antiviral and chemotactic activity. 2008.

Weck M, Galdiero S, Tarallo R, Carberry T, Falanga A, Galdiero M. Polyamide based peptidodendrimer conjugates. 2015.

Galdiero S, Scudiero O, Pessi A, Salvatore F. Cyclic beta defensins analogs for the treatment of infections. 2014.

Galdiero S, Galdiero, M M, Pedone C, Falanga A, Vitiello M. Method for delivery of molecules into intracellular targets. 2009.

Biomacromolecules, volume 20, issue 3, March 2019 Small, volume 9, no 6, March 2013 Protein Science, volume 13, no 6, June 2004